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Cannabinoids are a group of chemical compounds found in the cannabis plant that interact with the body’s endocannabinoid system (ECS), influencing various physiological processes.

See our post on the endocannabinoid system.

The most well-known cannabinoids are THC (Tetrahydrocannabinol) and CBD (Cannabidiol). THC is psychoactive and responsible for the “high” associated with cannabis use. It can offer pain relief, mood enhancement, and aid in sleep, but it may also cause anxiety and short-term memory impairment in some individuals.

CBD, on the other hand, does not produce a high and is renowned for its therapeutic properties. It’s commonly used to manage anxiety, pain, inflammation, and has shown promise in treating conditions like epilepsy. CBD can counteract some of THC’s psychoactive effects, making it appealing for medical use.

Other lesser-known cannabinoids include CBN (Cannabinol), CBG (Cannabigerol), and THCV (Tetrahydrocannabivarin), each with unique potential benefits. CBN is known for its sedative properties, CBG for its anti-inflammatory and neuroprotective effects, and THCV for appetite suppression and possible diabetes management.

When consumed, cannabinoids bind to receptor sites in the brain and body – mainly CB1 receptors in the central nervous system and CB2 receptors in peripheral organs and cells associated with the immune system. This binding action triggers various responses, leading to the diverse effects of cannabis.

Understanding cannabinoids is key to maximizing the therapeutic potential of cannabis and tailoring its use to individual needs and preferences.